Bromocriptine

Basic Information

CAS ID: 25614-03-3
Molecular Formula: C32H40BrN5O5
Molecular Weight: 654.6 g/mol
Monoisotopic Mass: 653.2213 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Bromocriptine | (+)-Bromocriptine | BROMOCRIPTINE MESYLATE | CB-154 | CB-154 MESYLATE | BROMOCRIPTINE MESILATE | PARLODEL | CYCLOSET
Analysis: Drug repositioning mechanism analysis

N O NH O N Br NH O OH N O

Compound Structure and Identifier

InChI: InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 See All
InChI Key: OZVBMTJYIDMWIL-AYFBDAFISA-N
Smiles: CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C See All
Molfile: Download

Related Target

Target ID Name Interaction
T0250 Prolactin inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 24448315 Target ID T0250
Uniprot ID Prolactin Name Prolactin
Model vitro,mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting Akt and STAT3

Trial Record 1

ClinicalTrial ID NCT02265484 Disease Liver fibrosis
Phase Not Applicable Status Completed
First Received October 16, 2014 Last Verified November 22, 2016
Sponsor Institute of Liver and Biliary Sciences, India

Related Link

PubChem: 31101
ChEMBL: CHEMBL493