| CAS ID: | 81093-37-0 |
| Molecular Formula: | C23H36O7 |
| Molecular Weight: | 424.5 g/mol |
| Monoisotopic Mass: | 424.2461 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | PRAVASTATIN SODIUM | LIPEMOL | PRAVASTATIN | CS-514 | EPTASTATIN SODIUM | LIPLAT | Pravachol | PRAVACHOL | LIPOSTAT | ELISOR | SQ-31,000 |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1 | See All |
| InChI Key: | TUZYXOIXSAXUGO-PZAWKZKUSA-N | |
| Smiles: | CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@@H]12 | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 17170375 | Target ID | |
| Uniprot ID | Name | ||
| Model | rat | Fibrosis Disease | Vascular fibrosis |
| Process I | attenue inflammation | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Trial Record 1
| ClinicalTrial ID | NCT01268202 | Disease | Fibrosis |
| Phase | Phase 2 | Status | Unknown |
| First Received | December 29, 2010 | Last Verified | June 10, 2016 |
| Sponsor | Gustave Roussy, Cancer Campus, Grand Paris | ||
Trial Record 2
| ClinicalTrial ID | NCT00467831 | Disease | Pulmonary fibrosis |
| Phase | Phase 1,Phase 2 | Status | Terminated |
| First Received | May 1, 2007 | Last Verified | August 2, 2013 |
| Sponsor | National Human Genome Research Institute (NHGRI) | ||
| PubChem: | 54687 |
| ChEMBL: | CHEMBL1144 |