CCG-222740

Basic Information

CAS ID: 1922098-69-8
Molecular Formula: C23H19ClF2N2O3
Molecular Weight: 444.9 g/mol
Monoisotopic Mass: 444 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

N F F O O O NH Cl

Compound Structure and Identifier

InChI: InChI=1S/C23H19ClF2N2O3/c24-18-6-8-19(9-7-18)27-21(29)17-12-23(25,26)14-28(13-17)22(30)16-4-1-3-15(11-16)20-5-2-10-31-20/h1-11,17H,12-14H2,(H,27,29) See All
InChI Key: PMTPYUTZAJWGPE-UHFFFAOYSA-N
Smiles: C1C(CN(CC1(F)F)C(=O)C2=CC=CC(=C2)C3=CC=CO3)C(=O)NC4=CC=C(C=C4)Cl See All
Molfile:

Related Target

Target ID Name Interaction
T0490 [F-actin]-monooxygenase MICAL2 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 28364121 Target ID T0490
Uniprot ID [F-actin]-monooxygenase MICAL2 Name [F-actin]-monooxygenase MICAL2
Model vitro,human Fibrosis Disease Scar
Process I
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting MRTF/SRF pathway

Related Link

PubChem: 121317937
ChEMBL: