| CAS ID: | 12705-41-8 |
| Molecular Formula: | C58H105N16Na5O28S5 |
| Molecular Weight: | 1749.8 g/mol |
| Monoisotopic Mass: | 1748.538 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | COLY-MYCIN | PROMIXIN | COLY-MYCIN M | COLIFIN 1 MIU | COLIFIN 2 MIU | W 1929 | COLOBREATHE | COLISTIMETHATE SODIUM |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C58H110N16O28S5.5Na/c1-9-35(6)12-10-11-13-46(77)65-38(14-20-59-28-103(88,89)90)53(82)74-48(37(8)76)58(87)70-41(17-23-62-31-106(97,98)99)50(79)68-43-19-25-64-57(86)47(36(7)75)73-54(83)42(18-24-63-32-107(100,101)102)67-49(78)39(15-21-60-29-104(91,92)93)69-55(84)44(26-33(2)3)72-56(85)45(27-34(4)5)71-52(81)40(66-51(43)80)16-22-61-30-105(94,95)96;;;;;/h33-45,47-48,59-63,75-76H,9-32H2,1-8H3,(H,64,86)(H,65,77)(H,66,80)(H,67,78)(H,68,79)(H,69,84)(H,70,87)(H,71,81)(H,72,85)(H,73,83)(H,74,82)(H,88,89,90)(H,91,92,93)(H,94,95,96)(H,97,98,99)(H,100,101,102);;;;;/q;5*+1/p-5 | See All |
| InChI Key: | IQWHCHZFYPIVRV-UHFFFAOYSA-I | |
| Smiles: | CCC(C)CCCCC(=O)NC(CCNCS(=O)(=O)[O-])C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)[O-])C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCNCS(=O)(=O)[O-])CC(C)C)CC(C)C)CCNCS(=O)(=O)[O-])CCNCS(=O)(=O)[O-])C(C)O.[Na+].[Na+].[Na+].[Na+].[Na+] | See All |
| Molfile: |
Trial Record 1
| ClinicalTrial ID | NCT01400750 | Disease | Cystic fibrosis |
| Phase | Phase 4 | Status | Completed |
| First Received | July 22, 2011 | Last Verified | August 4, 2011 |
| Sponsor | Universitaire Ziekenhuizen Leuven | ||
Trial Record 2
| ClinicalTrial ID | NCT01844778 | Disease | Cystic fibrosis |
| Phase | Phase 4 | Status | Completed |
| First Received | May 1, 2013 | Last Verified | July 27, 2016 |
| Sponsor | Novartis Pharmaceuticals | ||
Trial Record 3
| ClinicalTrial ID | NCT02113397 | Disease | Cystic fibrosis |
| Phase | Status | Terminated | |
| First Received | April 14, 2014 | Last Verified | March 12, 2018 |
| Sponsor | Dartmouth-Hitchcock Medical Center | ||
Trial Record 4
| ClinicalTrial ID | NCT02288429 | Disease | Cystic fibrosis |
| Phase | Status | Active, not recruiting | |
| First Received | November 11, 2014 | Last Verified | May 9, 2018 |
| Sponsor | University of Colorado, Denver | ||
Trial Record 5
| ClinicalTrial ID | NCT02113397 | Disease | Cystic fibrosis |
| Phase | Status | Terminated | |
| First Received | April 14, 2014 | Last Verified | March 12, 2018 |
| Sponsor | Dartmouth-Hitchcock Medical Center | ||
| PubChem: | |
| ChEMBL: | CHEMBL1201441 |