Ataluren

Basic Information

CAS ID: 775304-57-9
Molecular Formula: C15H9FN2O3
Molecular Weight: 284.3 g/mol
Monoisotopic Mass: 284.0597 g/mol
Class: Small Molecule
Natural Product: No
Other Names: ATALUREN | PTC124
Analysis: Drug repositioning mechanism analysis

HO O N O N F

Compound Structure and Identifier

InChI: InChI=1S/C15H9FN2O3/c16-12-7-2-1-6-11(12)14-17-13(18-21-14)9-4-3-5-10(8-9)15(19)20/h1-8H,(H,19,20) See All
InChI Key: OOUGLTULBSNHNF-UHFFFAOYSA-N
Smiles: OC(=O)c1cccc(c1)c2noc(n2)c3ccccc3F See All
Molfile: Download

Related Target

Related Fibrosis Property

Trial Record 1

ClinicalTrial ID NCT00234663 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received October 7, 2005 Last Verified January 13, 2009
Sponsor PTC Therapeutics

Trial Record 2

ClinicalTrial ID NCT00351078 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received July 12, 2006 Last Verified December 13, 2017
Sponsor PTC Therapeutics

Trial Record 3

ClinicalTrial ID NCT00803205 Disease Cystic fibrosis
Phase Status Completed
First Received December 5, 2008 Last Verified June 6, 2017
Sponsor PTC Therapeutics

Trial Record 4

ClinicalTrial ID NCT02107859 Disease Cystic fibrosis
Phase Phase 3 Status Terminated
First Received April 8, 2014 Last Verified January 28, 2019
Sponsor PTC Therapeutics

Trial Record 5

ClinicalTrial ID NCT01140451 Disease Cystic fibrosis
Phase Phase 3 Status Completed
First Received June 9, 2010 Last Verified December 15, 2017
Sponsor PTC Therapeutics

Trial Record 6

ClinicalTrial ID NCT02456103 Disease Cystic fibrosis
Phase Phase 3 Status Terminated
First Received May 28, 2015 Last Verified January 28, 2019
Sponsor PTC Therapeutics

Trial Record 7

ClinicalTrial ID NCT02139306 Disease Cystic fibrosis
Phase Phase 3 Status Unknown
First Received May 15, 2014 Last Verified November 26, 2015
Sponsor PTC Therapeutics

Trial Record 8

ClinicalTrial ID NCT03256968 Disease Cystic fibrosis
Phase Phase 4 Status Completed
First Received August 22, 2017 Last Verified January 14, 2019
Sponsor University of Alabama at Birmingham

Trial Record 9

ClinicalTrial ID NCT03256799 Disease Cystic fibrosis
Phase Phase 4 Status Completed
First Received August 22, 2017 Last Verified October 19, 2017
Sponsor University of Alabama at Birmingham

Trial Record 10

ClinicalTrial ID NCT00237380 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received October 12, 2005 Last Verified January 14, 2009
Sponsor PTC Therapeutics

Trial Record 11

ClinicalTrial ID NCT00458341 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received April 10, 2007 Last Verified April 2, 2009
Sponsor PTC Therapeutics

Related Link

PubChem: 11219835
ChEMBL: CHEMBL256997