VX-561

Basic Information

CAS ID: 1413431-07-8
Molecular Formula: C24H28N2O3
Molecular Weight: 401.6 g/mol
Monoisotopic Mass: 401.266 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

NH O NH O OH

Compound Structure and Identifier

InChI: InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)/i4D3,5D3,6D3 See All
InChI Key: PURKAOJPTOLRMP-ASMGOKTBSA-N
Smiles: CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C See All
Molfile:

Related Target

Related Fibrosis Property

Trial Record 1

ClinicalTrial ID NCT02951182 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received November 1, 2016 Last Verified August 15, 2018
Sponsor Vertex Pharmaceuticals Incorporated

Trial Record 2

ClinicalTrial ID NCT02971839 Disease Cystic fibrosis
Phase Phase 2 Status Terminated
First Received November 23, 2016 Last Verified August 15, 2018
Sponsor Vertex Pharmaceuticals Incorporated

Related Link

PubChem: 71470491
ChEMBL: