Gefapixant

Basic Information

CAS ID: 1015787-98-0
Molecular Formula: C14H19N5O4S
Molecular Weight: 353.4 g/mol
Monoisotopic Mass: 353.1158 g/mol
Class: Small Molecule
Natural Product: No
Other Names: RG1646 | R1646 | RO4926219 | AF-219 | GEFAPIXANT
Analysis: Drug repositioning mechanism analysis

O O N NH2 N NH2 S O O NH2

Compound Structure and Identifier

InChI: InChI=1S/C14H19N5O4S/c1-7(2)8-4-10(22-3)12(24(17,20)21)5-9(8)23-11-6-18-14(16)19-13(11)15/h4-7H,1-3H3,(H2,17,20,21)(H4,15,16,18,19) See All
InChI Key: HLWURFKMDLAKOD-UHFFFAOYSA-N
Smiles: COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(=O)(=O)N See All
Molfile: Download

Related Target

Related Fibrosis Property

Trial Record 1

ClinicalTrial ID NCT02477709 Disease Idiopathic pulmonary fibrosis
Phase Phase 2 Status Completed
First Received June 23, 2015 Last Verified May 16, 2017
Sponsor Afferent Pharmaceuticals, Inc.

Trial Record 2

ClinicalTrial ID NCT02502097 Disease Idiopathic pulmonary fibrosis
Phase Phase 2 Status Completed
First Received July 20, 2015 Last Verified May 31, 2017
Sponsor Afferent Pharmaceuticals, Inc.

Related Link

PubChem: 24764487
ChEMBL: CHEMBL3716057