Ambrisentan

Basic Information

CAS ID: 177036-94-1
Molecular Formula: C22H22N2O4
Molecular Weight: 378.4 g/mol
Monoisotopic Mass: 378.158 g/mol
Class: Small Molecule
Natural Product: No
Other Names: VOLIBRIS | AMBRISENTAN | LETAIRIS
Analysis: Drug repositioning mechanism analysis

O O N N O OH

Compound Structure and Identifier

InChI: InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1 See All
InChI Key: OUJTZYPIHDYQMC-LJQANCHMSA-N
Smiles: COC([C@H](Oc1nc(C)cc(C)n1)C(=O)O)(c2ccccc2)c3ccccc3 See All
Molfile: Download

Related Target

Related Fibrosis Property

Trial Record 1

ClinicalTrial ID NCT00879229 Disease Idiopathic pulmonary fibrosis
Phase Phase 3 Status Terminated
First Received April 9, 2009 Last Verified May 15, 2014
Sponsor Gilead Sciences

Trial Record 2

ClinicalTrial ID NCT00768300 Disease Idiopathic pulmonary fibrosis
Phase Phase 3 Status Terminated
First Received October 8, 2008 Last Verified April 8, 2014
Sponsor Gilead Sciences

Related Link

PubChem: 6918493
ChEMBL: CHEMBL1111