Lamivudine

Basic Information

CAS ID: 134678-17-4
Molecular Formula: C8H11N3O3S
Molecular Weight: 229.3 g/mol
Monoisotopic Mass: 229.0521 g/mol
Class: Small Molecule
Natural Product: No
Other Names: GR 109714X | EPIVIR | EPIVIR-HBV | LAMIVUDINE | ZEFFIX
Analysis: Drug repositioning mechanism analysis

H2N N O N S OH O

Compound Structure and Identifier

InChI: InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1 See All
InChI Key: JTEGQNOMFQHVDC-NKWVEPMBSA-N
Smiles: NC1=NC(=O)N(C=C1)[C@@H]2CS[C@H](CO)O2 See All
Molfile: Download

Related Target

Related Fibrosis Property

Trial Record 1

ClinicalTrial ID NCT02499562 Disease Liver fibrosis
Phase Phase 2 Status Unknown
First Received July 16, 2015 Last Verified July 16, 2015
Sponsor Shanghai Genomics, Inc.

Trial Record 2

ClinicalTrial ID NCT01718587 Disease Liver fibrosis
Phase Phase 1,Phase 2 Status Unknown
First Received October 31, 2012 Last Verified October 31, 2012
Sponsor General Hospital of Chinese Armed Police Forces

Trial Record 3

ClinicalTrial ID NCT01693679 Disease Liver fibrosis
Phase Phase 4 Status Unknown
First Received September 26, 2012 Last Verified September 26, 2012
Sponsor Shao-quan Zhang

Trial Record 4

ClinicalTrial ID NCT00490620 Disease Liver fibrosis
Phase Phase 2,Phase 3 Status Completed
First Received June 25, 2007 Last Verified November 1, 2007
Sponsor University of Alberta

Trial Record 5

ClinicalTrial ID NCT01720238 Disease Liver fibrosis
Phase Status Unknown
First Received November 2, 2012 Last Verified July 28, 2015
Sponsor Beijing Friendship Hospital

Trial Record 6

ClinicalTrial ID NCT00823550 Disease Liver fibrosis
Phase Phase 4 Status Unknown
First Received January 15, 2009 Last Verified December 16, 2010
Sponsor Yonsei University

Trial Record 7

ClinicalTrial ID NCT00275652 Disease Liver fibrosis
Phase Phase 3 Status Completed
First Received January 12, 2006 Last Verified March 23, 2011
Sponsor Mayo Clinic

Trial Record 8

ClinicalTrial ID NCT00076336 Disease Liver fibrosis
Phase Phase 3 Status Completed
First Received January 22, 2004 Last Verified September 5, 2011
Sponsor Novartis Pharmaceuticals

Trial Record 9

ClinicalTrial ID NCT01908660 Disease Liver fibrosis
Phase Status Completed
First Received July 26, 2013 Last Verified November 11, 2015
Sponsor Valme University Hospital

Trial Record 10

ClinicalTrial ID NCT02750059 Disease Cystic fibrosis
Phase Phase 2 Status Active, not recruiting
First Received April 25, 2016 Last Verified April 18, 2018
Sponsor South East Asia Research Collaboration with Hawaii

Related Link

PubChem: 60825
ChEMBL: CHEMBL141