| CAS ID: | 128-13-2 |
| Molecular Formula: | C24H40O4 |
| Molecular Weight: | 392.6 g/mol |
| Monoisotopic Mass: | 392.2927 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | URSODIOL | URSO 250 | URSOFALK | URSO FORTE | ACTIGALL | URSODEOXYCHOLIC ACID | URSODESOXYCHOLIC ACID | URDOX | CHOLURSO | URSO | URSOGAL | DESTOLIT |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1 | See All |
| InChI Key: | RUDATBOHQWOJDD-UZVSRGJWSA-N | |
| Smiles: | C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | See All |
| Molfile: | Download |
Trial Record 1
| ClinicalTrial ID | NCT00470171 | Disease | Liver fibrosis |
| Phase | Phase 2 | Status | Completed |
| First Received | May 7, 2007 | Last Verified | February 3, 2009 |
| Sponsor | Axcan Pharma | ||
Trial Record 2
| ClinicalTrial ID | NCT02916290 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Unknown |
| First Received | September 27, 2016 | Last Verified | September 27, 2016 |
| Sponsor | Xijing Hospital of Digestive Diseases | ||
Trial Record 3
| ClinicalTrial ID | NCT02823366 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Unknown |
| First Received | July 6, 2016 | Last Verified | July 7, 2016 |
| Sponsor | Xijing Hospital of Digestive Diseases | ||
Trial Record 4
| ClinicalTrial ID | NCT02823353 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Unknown |
| First Received | July 6, 2016 | Last Verified | July 7, 2016 |
| Sponsor | Xijing Hospital of Digestive Diseases | ||
Trial Record 5
| ClinicalTrial ID | NCT01904058 | Disease | Liver fibrosis |
| Phase | Phase 2 | Status | Completed |
| First Received | July 22, 2013 | Last Verified | July 6, 2016 |
| Sponsor | Shire | ||
Trial Record 6
| ClinicalTrial ID | NCT01857284 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Completed |
| First Received | May 20, 2013 | Last Verified | May 20, 2013 |
| Sponsor | Beijing Friendship Hospital | ||
Trial Record 7
| ClinicalTrial ID | NCT01510860 | Disease | Liver fibrosis |
| Phase | Phase 4 | Status | Completed |
| First Received | January 18, 2012 | Last Verified | January 18, 2012 |
| Sponsor | Dr. Falk Pharma GmbH | ||
Trial Record 8
| ClinicalTrial ID | NCT01440309 | Disease | Liver fibrosis |
| Phase | Phase 1 | Status | Unknown |
| First Received | September 26, 2011 | Last Verified | August 3, 2012 |
| Sponsor | Robert Chunhua Zhao, MD, PhD | ||
Trial Record 9
| ClinicalTrial ID | NCT01141296 | Disease | Liver fibrosis |
| Phase | Phase 2 | Status | Withdrawn |
| First Received | June 10, 2010 | Last Verified | April 2, 2014 |
| Sponsor | University of Miami | ||
Trial Record 10
| ClinicalTrial ID | NCT00805805 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Completed |
| First Received | December 10, 2008 | Last Verified | May 23, 2017 |
| Sponsor | George Brewer | ||
Trial Record 11
| ClinicalTrial ID | NCT00746486 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Terminated |
| First Received | September 4, 2008 | Last Verified | February 8, 2017 |
| Sponsor | Dr. Falk Pharma GmbH | ||
Trial Record 12
| ClinicalTrial ID | NCT00550862 | Disease | Liver fibrosis |
| Phase | Phase 2 | Status | Completed |
| First Received | October 30, 2007 | Last Verified | February 14, 2012 |
| Sponsor | Intercept Pharmaceuticals | ||
Trial Record 13
| ClinicalTrial ID | NCT00108355 | Disease | Liver fibrosis |
| Phase | Phase 4 | Status | Completed |
| First Received | April 15, 2005 | Last Verified | March 6, 2014 |
| Sponsor | US Department of Veterans Affairs | ||
Trial Record 14
| ClinicalTrial ID | NCT00004784 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Completed |
| First Received | February 25, 2000 | Last Verified | June 24, 2005 |
| Sponsor | National Center for Research Resources (NCRR) | ||
Trial Record 15
| ClinicalTrial ID | NCT00004748 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Completed |
| First Received | February 25, 2000 | Last Verified | June 24, 2005 |
| Sponsor | National Center for Research Resources (NCRR) | ||
Trial Record 16
| ClinicalTrial ID | NCT01331785 | Disease | Liver fibrosis |
| Phase | Not Applicable | Status | Withdrawn |
| First Received | April 8, 2011 | Last Verified | July 31, 2013 |
| Sponsor | The Cleveland Clinic | ||
| PubChem: | 31401 |
| ChEMBL: | CHEMBL1551 |