Midodrine

Basic Information


CAS ID: 42794-76-3
Molecular Formula: C12H18N2O4
Molecular Weight: 254.3 g/mol
Monoisotopic Mass: 254.1267 g/mol
Class: Small Molecule
Natural Product: No
Other Names: ST. PETER 224 | ORVATEN | GUTRON | BRAMOX | PROAMATINE | MIDODRINE HYDROCHLORIDE | Midodrine | A-4020 LINZ | ST-1085 | MIDON | ST 1085 [AS THE BASE]
Analysis: Drug repositioning mechanism analysis

O O OH NH O NH2


Compound Structure and Identifier


InChI: InChI=1S/C12H18N2O4/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16) See All
InChI Key: PTKSEFOSCHHMPD-UHFFFAOYSA-N
Smiles: COc1ccc(OC)c(c1)C(O)CNC(=O)CN See All
Molfile: Download


Related Target



Related Fibrosis Property


Trial Record 1

ClinicalTrial ID NCT01587222 Disease Renal fibrosis
Phase Phase 2 Status Withdrawn
First Received April 30, 2012 Last Verified February 15, 2019
Sponsor Anna Cruceta

Trial Record 2

ClinicalTrial ID NCT03144713 Disease Liver fibrosis
Phase Not Applicable Status Completed
First Received May 9, 2017 Last Verified September 5, 2018
Sponsor Institute of Liver and Biliary Sciences, India

Trial Record 3

ClinicalTrial ID NCT02173288 Disease Liver fibrosis
Phase Phase 2,Phase 3 Status Completed
First Received June 24, 2014 Last Verified September 19, 2017
Sponsor Postgraduate Institute of Medical Education and Research

Trial Record 4

ClinicalTrial ID NCT01133795 Disease Liver fibrosis
Phase Phase 2 Status Completed
First Received May 31, 2010 Last Verified August 18, 2016
Sponsor Hospital Clinic of Barcelona

Trial Record 5

ClinicalTrial ID NCT00108355 Disease Liver fibrosis
Phase Phase 4 Status Completed
First Received April 15, 2005 Last Verified March 6, 2014
Sponsor US Department of Veterans Affairs

Trial Record 6

ClinicalTrial ID NCT00742339 Disease Liver fibrosis
Phase Phase 2,Phase 3 Status Terminated
First Received August 27, 2008 Last Verified October 15, 2014
Sponsor University of Padova

Related Link


PubChem: 4195
ChEMBL: CHEMBL1201212