| CAS ID: | 1353900-92-1 |
| Molecular Formula: | C57H65F5N10O8 |
| Molecular Weight: | 1113.2 g/mol |
| Monoisotopic Mass: | 1112.4907 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | ABT-530 | PIBRENTASVIR | A-1325912.0 |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C57H65F5N10O8/c1-29(77-3)49(67-56(75)79-5)54(73)70-19-7-9-47(70)52-63-41-25-35(37(59)27-43(41)65-52)45-15-16-46(72(45)34-23-39(61)51(40(62)24-34)69-21-17-32(18-22-69)31-11-13-33(58)14-12-31)36-26-42-44(28-38(36)60)66-53(64-42)48-10-8-20-71(48)55(74)50(30(2)78-4)68-57(76)80-6/h11-14,23-30,32,45-50H,7-10,15-22H2,1-6H3,(H,63,65)(H,64,66)(H,67,75)(H,68,76)/t29-,30-,45-,46-,47+,48+,49+,50+/m1/s1 | See All |
| InChI Key: | VJYSBPDEJWLKKJ-NLIMODCCSA-N | |
| Smiles: | CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c2nc3cc([C@H]4CC[C@@H](N4c5cc(F)c(N6CCC(CC6)c7ccc(F)cc7)c(F)c5)c8cc9nc([nH]c9cc8F)[C@@H]%10CCCN%10C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC)c(F)cc3[nH]2 | See All |
| Molfile: | Download |
Trial Record 1
| ClinicalTrial ID | NCT03089944 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Active, not recruiting |
| First Received | March 24, 2017 | Last Verified | March 22, 2019 |
| Sponsor | AbbVie | ||
Trial Record 2
| ClinicalTrial ID | NCT01995071 | Disease | Liver fibrosis |
| Phase | Phase 2 | Status | Completed |
| First Received | November 26, 2013 | Last Verified | October 16, 2017 |
| Sponsor | AbbVie | ||
Trial Record 3
| ClinicalTrial ID | NCT03235349 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Completed |
| First Received | August 1, 2017 | Last Verified | March 13, 2019 |
| Sponsor | AbbVie | ||
Trial Record 4
| ClinicalTrial ID | NCT02738138 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Completed |
| First Received | April 14, 2016 | Last Verified | May 9, 2018 |
| Sponsor | AbbVie | ||
Trial Record 5
| ClinicalTrial ID | NCT02642432 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Completed |
| First Received | December 30, 2015 | Last Verified | October 26, 2017 |
| Sponsor | AbbVie | ||
Trial Record 6
| ClinicalTrial ID | NCT03219216 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Active, not recruiting |
| First Received | July 17, 2017 | Last Verified | November 1, 2018 |
| Sponsor | AbbVie | ||
| PubChem: | 58031952 |
| ChEMBL: | CHEMBL3545123 |