Eltrombopag

Basic Information


CAS ID: 496775-61-2
Molecular Formula: C25H22N4O4
Molecular Weight: 442.5 g/mol
Monoisotopic Mass: 442.1641 g/mol
Class: Small Molecule
Natural Product: No
Other Names: ELTROMBOPAG OLAMINE | ELTROMBOPAG | Revolade | SB-497115-GR | PROMACTA | Promacta | REVOLADE | Eltrombopag olamine
Analysis: Drug repositioning mechanism analysis

N N O N NH OH O OH


Compound Structure and Identifier


InChI: InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22- See All
InChI Key: XDXWLKQMMKQXPV-QYQHSDTDSA-N
Smiles: CC1=NN(C(=O)/C/1=N\Nc2cccc(c2O)c3cccc(c3)C(=O)O)c4ccc(C)c(C)c4 See All
Molfile: Download


Related Target



Related Fibrosis Property


Trial Record 1

ClinicalTrial ID NCT01443351 Disease Bone marrow fibrosis
Phase Status Recruiting
First Received September 29, 2011 Last Verified February 5, 2015
Sponsor Zealand University Hospital

Trial Record 2

ClinicalTrial ID NCT00961064 Disease Bone marrow fibrosis
Phase Phase 2 Status Active, not recruiting
First Received August 18, 2009 Last Verified February 15, 2019
Sponsor National Heart, Lung, and Blood Institute (NHLBI)

Related Link


PubChem: 135449332
ChEMBL: CHEMBL461101