Growth differentiation factor-15

Basic Information


Uniprot ID: Q99988
Secondary ID: O14629
Symbol: GDF15
Other Name: MIC1,GDF-15,Macrophage inhibitory cytokine 1,MIC-1,NSAID-activated gene 1 protein,NAG-1,NSAID-regulated gene 1 protein,NRG-1,Placental TGF-beta,Placental bone morphogenetic protein,Prostate differentiation factor
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Cytokine,Growth factor


Target Classification


Category I Category II Category III
Extracellular Growth factor and receptor TGF-beta superfamily

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28872977 Compound ID
CAS Name
Model human Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 29222479 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism