Uniprot ID: | Q99988 |
Secondary ID: | O14629 |
Symbol: | GDF15 |
Other Name: | MIC1,GDF-15,Macrophage inhibitory cytokine 1,MIC-1,NSAID-activated gene 1 protein,NAG-1,NSAID-regulated gene 1 protein,NRG-1,Placental TGF-beta,Placental bone morphogenetic protein,Prostate differentiation factor |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Cytokine,Growth factor |
Category I | Category II | Category III |
---|---|---|
Extracellular | Growth factor and receptor | TGF-beta superfamily |
Reference Record 1
PubMed ID | 28872977 | Compound ID | |
CAS | Name | ||
Model | human | Fibrosis Disease | Systemic sclerosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism |
Reference Record 2
PubMed ID | 29222479 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | attenue inflammation | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |