Activin receptor type-2A

Basic Information


Uniprot ID: P27037
Secondary ID: B2RAB8
Symbol: ACVR2A
Other Name: ACVR2,Activin receptor type IIA,ACTR-IIA,ACTRIIA
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Kinase,Receptor,Serine/threonine-protein kinase,Transferase


Target Classification


Category I Category II Category III
Extracellular Growth factor and receptor TGF-beta superfamily

Related Compound


Target ID Name Interaction
D1046 RAP-011 mimic

Fibrosis Related Property


Reference Record 1

PubMed ID 27165838 Compound ID D1046
CAS Name RAP-011
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting ActRIIA signaling