Serine/threonine-protein kinase receptor R3

Basic Information


Uniprot ID: P37023
Secondary ID: A6NGA8
Symbol: ACVRL1
Other Name: ACVRLK1,SKR3,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Kinase,Receptor,Serine/threonine-protein kinase,Transferase


Target Classification


Category I Category II Category III
Extracellular Growth factor and receptor TGF-beta superfamily

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 21344387 Compound ID
CAS Name
Model vitro Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting TGF-β/Smad1 signaling