Uniprot ID: | P37023 |
Secondary ID: | A6NGA8 |
Symbol: | ACVRL1 |
Other Name: | ACVRLK1,SKR3,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Kinase,Receptor,Serine/threonine-protein kinase,Transferase |
Category I | Category II | Category III |
---|---|---|
Extracellular | Growth factor and receptor | TGF-beta superfamily |
Reference Record 1
PubMed ID | 21344387 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Systemic sclerosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β/Smad1 signaling |