Left-right determination factor 2

Basic Information


Uniprot ID: O00292
Secondary ID: B3KNH4
Symbol: LEFTY2
Other Name: EBAF,Endometrial bleeding-associated factor,Left-right determination factor A,Protein lefty-2,Protein lefty-A,Transforming growth factor beta-4,TGF-beta-4
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Cytokine,Developmental protein,Growth factor


Target Classification


Category I Category II Category III
Extracellular Growth factor and receptor TGF-beta superfamily

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 20738296 Compound ID
CAS Name
Model human Fibrosis Disease Renal fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 20157767 Compound ID
CAS Name
Model vitro Fibrosis Disease Renal fibrosis
Process I
Process II EMT
Process III
Mechanism Targeting TGF-β1/Smads signaling pathway