Uniprot ID: | O00292 |
Secondary ID: | B3KNH4 |
Symbol: | LEFTY2 |
Other Name: | EBAF,Endometrial bleeding-associated factor,Left-right determination factor A,Protein lefty-2,Protein lefty-A,Transforming growth factor beta-4,TGF-beta-4 |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Cytokine,Developmental protein,Growth factor |
Category I | Category II | Category III |
---|---|---|
Extracellular | Growth factor and receptor | TGF-beta superfamily |
Reference Record 1
PubMed ID | 20738296 | Compound ID | |
CAS | Name | ||
Model | human | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism |
Reference Record 2
PubMed ID | 20157767 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | EMT | ||
Process III | |||
Mechanism | Targeting TGF-β1/Smads signaling pathway |