Fibroblast growth factor 1

Basic Information


Uniprot ID: P05230
Secondary ID: B2R5T0
Symbol: FGF1
Other Name: FGFA,FGF-1,Acidic fibroblast growth factor,aFGF,Endothelial cell growth factor,ECGF,Heparin-binding growth factor 1,HBGF-1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Developmental protein,Growth factor,Heparin-binding,Mitogen


Target Classification


Category I Category II Category III
Extracellular Growth factor and receptor FGF family

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 20495078 Compound ID
CAS Name
Model vitro Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II EMT
Process III
Mechanism Targeting MEK-dependent signaling

Reference Record 2

PubMed ID 14507672 Compound ID
CAS Name
Model mice Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation
Process III prevenet collagen deposition
Mechanism