Insulin-like growth factor-binding protein 7

Basic Information


Uniprot ID: Q16270
Secondary ID: B4E1N2
Symbol: IGFBP7
Other Name: MAC25,IBP-7,IGF-binding protein 7,IGFBP-7,IGFBP-rP1,MAC25 protein,PGI2-stimulating factor,Prostacyclin-stimulating factor,Tumor-derived adhesion factor,TAF
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Growth factor binding


Target Classification


Category I Category II Category III
Extracellular Growth factor and receptor Insulin and receptor family

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 19598300 Compound ID
CAS Name
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation,myofibroblasts differentiation,HSCs apoptosis
Process III prevenet collagen deposition
Mechanism