| Uniprot ID: | P13725 |
| Secondary ID: | Q6FHP8, Q9UCP6 |
| Symbol: | OSM |
| Other Name: | |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: | Cytokine,Mitogen |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Cytokine and receptor | Interleukin and receptor family |
Reference Record 1
| PubMed ID | 26146616 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | cells apoptosis | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting VEGF and bFGF | ||
Reference Record 2
| PubMed ID | 23668543 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Pulmonary fibrosis |
| Process I | |||
| Process II | fibroblasts differentiation,fibroblasts migration | ||
| Process III | |||
| Mechanism | |||
Reference Record 3
| PubMed ID | 22051730 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Bone marrow fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation | ||
| Process III | |||
| Mechanism | Targeting STAT5 and PI3-kinase | ||
Reference Record 4
| PubMed ID | 20626292 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human,mice | Fibrosis Disease | Renal fibrosis |
| Process I | attenue inflammation | ||
| Process II | EMT | ||
| Process III | |||
| Mechanism | |||