Interleukin-13

Basic Information

Uniprot ID: P35225
Secondary ID: O43644, Q4VB52, Q9UDC7
Symbol: IL13
Other Name: NC30
Class: Single Protein
Type: pro/anti-fibrotic
Molecular Function: Cytokine

Target Classification

Category I Category II Category III
Extracellular Cytokine and receptor Interleukin and receptor family

Related Compound

Target ID Name Interaction
D0923 Tralokinumab binder

Fibrosis Related Property

Reference Record 1

PubMed ID 28004808 Compound ID
CAS Name
Model mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 27125685 Compound ID
CAS Name
Model mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 27125685 Compound ID
CAS Name
Model mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 24325475 Compound ID D0923
CAS 1044515-88-9 Name Tralokinumab
Model human,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 22245215 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III
Mechanism

Reference Record 6

PubMed ID 18830273 Compound ID
CAS Name
Model mice Fibrosis Disease Skin fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 7

PubMed ID 17766435 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 8

PubMed ID 15566951 Compound ID
CAS Name
Model mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 9

PubMed ID 15271999 Compound ID
CAS Name
Model vitro Fibrosis Disease Fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 10

PubMed ID 12928422 Compound ID
CAS Name
Model mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 11

PubMed ID 11714828 Compound ID
CAS Name
Model mice Fibrosis Disease Peribronchial fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 12

PubMed ID 11714828 Compound ID
CAS Name
Model mice Fibrosis Disease Peribronchial fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 13

PubMed ID 11290806 Compound ID
CAS Name
Model mice Fibrosis Disease Fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism