| Uniprot ID: | Q9GZX6 |
| Secondary ID: | |
| Symbol: | IL22 |
| Other Name: | ILTIF,IL-22,Cytokine Zcyto18,IL-10-related T-cell-derived-inducible factor,IL-TIF |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: | Cytokine |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Cytokine and receptor | Interleukin and receptor family |
Reference Record 1
| PubMed ID | 27819314 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSC proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting miR-200a | ||
Reference Record 2
| PubMed ID | 27123854 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs proliferation,HSCs activation | ||
| Process III | |||
| Mechanism | |||
Reference Record 3
| PubMed ID | 22473749 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation,HSCs apoptosis | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting STAT3 | ||
Reference Record 4
| PubMed ID | 20220096 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||