| Uniprot ID: | Q8NEV9 |
| Secondary ID: | A0N0L2, Q6P676 |
| Symbol: | IL27 |
| Other Name: | IL27A,IL-27 subunit alpha,IL-27-A,IL27-A,Interleukin-30,p28 |
| Class: | Single Protein |
| Type: | anti-fibrotic |
| Molecular Function: | Antiviral protein,Cytokine |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Cytokine and receptor | Interleukin and receptor family |
Reference Record 1
| PubMed ID | 26776832 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Pulmonary fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation,fibroblasts differentiation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting JAK/STAT and TGF-β/Smad signaling | ||
Reference Record 2
| PubMed ID | 25351459 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Liver fibrosis |
| Process I | attenue inflammation | ||
| Process II | HSCs activation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting NKG2D-rae1 interaction | ||