| Uniprot ID: | P50591 |
| Secondary ID: | A1Y9B3 |
| Symbol: | TNFSF10 |
| Other Name: | APO2L,Apo-2 ligand,Apo-2L,TNF-related apoptosis-inducing ligand,Protein TRAIL, |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: | Cytokine |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Cytokine and receptor | TNF family |
Reference Record 1
| PubMed ID | 27885847 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting DR5 receptor | ||
Reference Record 2
| PubMed ID | 24610963 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Renal fibrosis |
| Process I | attenue inflammation | ||
| Process II | cells apoptosis | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 3
| PubMed ID | 19470406 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | cells apoptosis | ||
| Process III | |||
| Mechanism | Targeting PI3K/Akt-FoxO signaling pathway | ||
Reference Record 4
| PubMed ID | 18220275 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation,cells apoptosis | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||