Uniprot ID: | Q9NP84 |
Secondary ID: | D3DUA6, Q9HCS0 |
Symbol: | TNFRSF12A |
Other Name: | FN14,Fibroblast growth factor-inducible immediate-early response protein 14,FGF-inducible 14,Tweak-receptor,TweakR, |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Developmental protein,Receptor |
Category I | Category II | Category III |
---|---|---|
Extracellular | Cytokine and receptor | TNF family |
Reference Record 1
PubMed ID | 26945694 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Systemic sclerosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism |
Reference Record 2
PubMed ID | 26625141 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Skin fibrosis |
Process I | |||
Process II | fibroblasts activation | ||
Process III | |||
Mechanism |
Reference Record 3
PubMed ID | 23325387 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | fibroblasts proliferation,myofibroblasts differentiation | ||
Process III | prevenet collagen deposition | ||
Mechanism |