C-C chemokine receptor type 2

Basic Information

Uniprot ID: P41597
Secondary ID: A0AVQ3
Symbol: CCR2
Other Name: CMKBR2,C-C CKR-2,CC-CKR-2,CCR-2,CCR2,Monocyte chemoattractant protein 1 receptor,MCP-1-R,
Class: Single Protein
Type: pro-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer

Target Classification

Category I Category II Category III
Extracellular Cytokine and receptor Chemokine

Related Compound

Fibrosis Related Property

Reference Record 1

PubMed ID 28627412 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting PI3K-AKT-mTOR signaling

Reference Record 2

PubMed ID 27271610 Compound ID
CAS Name
Model Fibrosis Disease Pancreatic fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 3

PubMed ID 18541733 Compound ID
CAS Name
Model mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 15601671 Compound ID
CAS Name
Model mice Fibrosis Disease Muscle fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 11884467 Compound ID
CAS Name
Model mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 6

PubMed ID 11884467 Compound ID
CAS Name
Model mice Fibrosis Disease Fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 7

PubMed ID 11373340 Compound ID
CAS Name
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III
Mechanism