C-C motif chemokine 2

Basic Information

Uniprot ID: P13500
Secondary ID: B2R4V3, Q9UDF3
Symbol: CCL2
Other Name: MCP1,HC11,Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor,MCAF,Monocyte chemotactic protein 1,MCP-1,Monocyte secretory protein JE,Small-inducible cytokine A2
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Cytokine

Target Classification

Category I Category II Category III
Extracellular Cytokine and receptor Chemokine

Related Compound

Target ID Name Interaction
D0412 Bindarit inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 28267084 Compound ID
CAS Name
Model human Fibrosis Disease Liver fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 27856463 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 22245215 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III
Mechanism

Reference Record 4

PubMed ID 19628782 Compound ID D0412
CAS 130641-38-2 Name Bindarit
Model vitro,pig Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 19546247 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 6

PubMed ID 17039283 Compound ID
CAS Name
Model vitro Fibrosis Disease Joint fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 7

PubMed ID 16095529 Compound ID
CAS Name
Model human Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 8

PubMed ID 11373340 Compound ID
CAS Name
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III
Mechanism