Beta-2 adrenergic receptor

Basic Information

Uniprot ID:	P07550
Secondary ID:	B0LPE4
Symbol:	ADRB2
Other Name:	ADRB2R,Beta-2 adrenoreceptor,Beta-2 adrenoceptor
Class:	Single Protein
Type:	anti-fibrotic
Molecular Function:	G-protein coupled receptor,Receptor,Transducer

Target Classification

Category I	Category II	Category III
Extracellular	G protein-coupled receptor	Adrenergic receptor

Related Compound

Target ID	Name	Interaction
D0012	Olodaterol	agonist
D0431	Metoprolol	antagonist

Fibrosis Related Property

Reference Record 1

PubMed ID	28810065	Compound ID	D0012
CAS	868049-49-4	Name	Olodaterol
Model	vitro	Fibrosis Disease	Pulmonary fibrosis
Process I
Process II	myofibroblasts activation,fibroblasts proliferation
Process III
Mechanism

Reference Record 2

PubMed ID	18632114	Compound ID	D0431
CAS	51384-51-1	Name	Metoprolol
Model	mice	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism