Beta-3 adrenergic receptor

Basic Information

Uniprot ID:	P13945
Secondary ID:	Q4JFT4
Symbol:	ADRB3
Other Name:	ADRB3R,Beta-3 adrenoreceptor,Beta-3 adrenoceptor
Class:	Single Protein
Type:	pro/anti-fibrotic
Molecular Function:	G-protein coupled receptor,Receptor,Transducer

Target Classification

Category I	Category II	Category III
Extracellular	G protein-coupled receptor	Adrenergic receptor

Related Compound

Target ID	Name	Interaction
D0160	L748337	antagonist
D0261	BRL37344	agonist

Fibrosis Related Property

Reference Record 1

PubMed ID	26828873	Compound ID	D0160
CAS	244192-94-7	Name	L748337
Model	dog	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID	24911015	Compound ID	D0261
CAS	116049-78-6	Name	BRL37344
Model	mice	Fibrosis Disease	Cardiac fibrosis
Process I
Process II	cells apoptosis
Process III	prevenet collagen deposition
Mechanism