Adenosine receptor A2b

Basic Information

Uniprot ID: P29275
Secondary ID:
Symbol: ADORA2B
Other Name:
Class: Single Protein
Type: pro/anti-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer

Target Classification

Category I Category II Category III
Extracellular G protein-coupled receptor Adenosine receptor

Related Compound

Target ID Name Interaction
D0292 GS-6201 antagonist
D0413 MRS1754 antagonist
D0542 Capadenoson agonist
D0543 NECA agonist
D0544 BAY60-6583 agonist

Fibrosis Related Property

Reference Record 1

PubMed ID 28344125 Compound ID D0542
CAS 544417-40-5 Name Capadenoson
Model vitro,rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 28344125 Compound ID D0543
CAS 35920-39-9 Name NECA
Model vitro,rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 3

PubMed ID 28344125 Compound ID D0544
CAS 910487-58-0 Name BAY60-6583
Model vitro,rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 4

PubMed ID 25498034 Compound ID
CAS Name
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 24120874 Compound ID D0292
CAS 752222-83-6 Name GS-6201
Model vitro,rat Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 6

PubMed ID 19858092 Compound ID D0413
CAS 264622-58-4 Name MRS1754
Model vitro,mice Fibrosis Disease Penile fibrosis
Process I
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism