Proto-oncogene Mas

Basic Information


Uniprot ID: P04201
Secondary ID: E1P5B3, Q2TBC9, Q6FG47
Symbol: MAS1
Other Name: MAS
Class: Single Protein
Type: pro/anti-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer


Target Classification


Category I Category II Category III
Extracellular G protein-coupled receptor Angiotensin receptor

Related Compound


Target ID Name Interaction
D0978 A779 antagonist

Fibrosis Related Property


Reference Record 1

PubMed ID 28656296 Compound ID
CAS Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting ACE2-Ang-MasR axis

Reference Record 2

PubMed ID 27592222 Compound ID D0978
CAS 159432-28-7 Name A779
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting ACE2-Ang-(1-7)-Mas and KCa3.1 channel