Sphingosine 1-phosphate receptor 1

Basic Information


Uniprot ID: P21453
Secondary ID: D3DT66, Q9BYY4, Q9NYN8
Symbol: S1PR1
Other Name: CHEDG1,S1P receptor 1,S1P1,Endothelial differentiation G-protein coupled receptor 1,Sphingosine 1-phosphate receptor Edg-1,S1P receptor Edg-1,
Class: Single Protein
Type: anti-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer


Target Classification


Category I Category II Category III
Extracellular G protein-coupled receptor Edg receptor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 26961351 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II myofibroblasts activation,myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism