Sphingosine 1-phosphate receptor 2

Basic Information

Uniprot ID:	O95136
Secondary ID:	Q86UN8
Symbol:	S1PR2
Other Name:	EDG5,S1P receptor 2,S1P2,Endothelial differentiation G-protein coupled receptor 5,Sphingosine 1-phosphate receptor Edg-5,S1P receptor Edg-5
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	G-protein coupled receptor,Receptor,Transducer

Target Classification

Category I	Category II	Category III
Extracellular	G protein-coupled receptor	Edg receptor

Related Compound

Target ID	Name	Interaction
D0549	JTE-013	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	28120434	Compound ID	D0549
CAS	383150-41-2	Name	JTE-013
Model	vitro,mice	Fibrosis Disease	Liver fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism	Targeting NF-κB signaling

Reference Record 2

PubMed ID	26534962	Compound ID	D0549
CAS	383150-41-2	Name	JTE-013
Model	vitro	Fibrosis Disease	Liver fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism