Sphingosine 1-phosphate receptor 5

Basic Information


Uniprot ID: Q9H228
Secondary ID: Q6NW11
Symbol: S1PR5
Other Name: EDG8,S1P receptor 5,S1P5,Endothelial differentiation G-protein-coupled receptor 8,Sphingosine 1-phosphate receptor Edg-8,S1P receptor Edg-8
Class: Single Protein
Type: pro/anti-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer


Target Classification


Category I Category II Category III
Extracellular G protein-coupled receptor Edg receptor

Related Compound


Target ID Name Interaction
D0101 Fingolimod agonist

Fibrosis Related Property


Reference Record 1

PubMed ID 24679864 Compound ID D0101
CAS 162359-55-9 Name Fingolimod
Model mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II myofibroblasts accumulation
Process III
Mechanism

Reference Record 2

PubMed ID 29033951 Compound ID
CAS Name
Model mice Fibrosis Disease Systemic sclerosis
Process I attenue inflammation
Process II
Process III
Mechanism