Lysophosphatidic acid receptor 3

Basic Information


Uniprot ID: Q9UBY5
Secondary ID: A0AVA3
Symbol: LPAR3
Other Name: EDG7,LPA receptor 3,LPA-3,Lysophosphatidic acid receptor Edg-7
Class: Single Protein
Type: pro-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer


Target Classification


Category I Category II Category III
Extracellular G protein-coupled receptor Edg receptor

Related Compound


Target ID Name Interaction
D0373 VPC12249 antagonist

Fibrosis Related Property


Reference Record 1

PubMed ID 21545790 Compound ID D0373
CAS 403520-23-0 Name VPC12249
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting CTGF