Melanin-concentrating hormone receptor 1

Basic Information

Uniprot ID:	Q99705
Secondary ID:	B2RBX6
Symbol:	MCHR1
Other Name:	GPR24,MCH receptor 1,MCH-R1,MCHR-1,G-protein coupled receptor 24,MCH-1R,MCH1R,MCHR,SLC-1,Somatostatin receptor-like protein
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	G-protein coupled receptor,Receptor,Transducer

Target Classification

Category I	Category II	Category III
Extracellular	G protein-coupled receptor	Other peptide receptor

Related Compound

Target ID	Name	Interaction
D0143	2(1H)-Pyridinone, 1-(2-cyclopropyl-3-methyl-2H-indazol-5-yl)-4-[[5-(trifluoromethyl)-3-thienyl]methoxy]-	antagonist

Fibrosis Related Property

Reference Record 1

PubMed ID	27986627	Compound ID	D0143
CAS	1643965-77-8	Name	2(1H)-Pyridinone, 1-(2-cyclopropyl-3-methyl-2H-indazol-5-yl)-4-[[5-(trifluoromethyl)-3-thienyl]methoxy]-
Model	mice,rat	Fibrosis Disease	Liver fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism