| Uniprot ID: | P13569 |
| Secondary ID: | Q20BG8 |
| Symbol: | CFTR |
| Other Name: | ABCC7,CFTR,ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel |
| Class: | Single Protein |
| Type: | pro-fibrotic |
| Molecular Function: | Chloride channel,Hydrolase,Ion channel |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Ion channel protein | Chloride channel |
Reference Record 1
| PubMed ID | 28701694 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
| Process I | |||
| Process II | EMT | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Wnt/β-catenin signaling | ||
Reference Record 2
| PubMed ID | 26488271 | Compound ID | |
| CAS | Name | ||
| Model | vitro,pig | Fibrosis Disease | Cystic fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 3
| PubMed ID | 21826241 | Compound ID | |
| CAS | Name | ||
| Model | human | Fibrosis Disease | Cystic fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||