Uniprot ID: | Q02763 |
Secondary ID: | A8K6W0 |
Symbol: | TEK |
Other Name: | TIE2,Endothelial tyrosine kinase,Tunica interna endothelial cell kinase,Tyrosine kinase with Ig and EGF homology domains-2,Tyrosine-protein kinase receptor TEK,Tyrosine-protein kinase receptor TIE-2,hTIE2,p140 TEK, |
Class: | Single Protein |
Type: | anti-fibrotic |
Molecular Function: | Kinase,Receptor,Transferase,Tyrosine-protein kinase |
Category I | Category II | Category III |
---|---|---|
Extracellular | Other membrane receptor | Kinase membrance receptor |
Reference Record 1
PubMed ID | 28545512 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Systemic sclerosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism | Targeting Ang/Tie2 balance |
Reference Record 2
Reference Record 3
PubMed ID | 25302785 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation | ||
Process III | |||
Mechanism |