Renin receptor

Basic Information


Uniprot ID: O75787
Secondary ID: B7Z9I3
Symbol: ATP6AP2
Other Name: ATP6IP2,ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,ER-localized type I transmembrane adaptor,Embryonic liver differentiation factor 10,N14F,Reninprorenin receptor,Vacuolar ATP synthase membrane sector-associated protein M8-9,ATP6M8-9,V-ATPase M8.9 subunit
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Receptor


Target Classification


Category I Category II Category III
Extracellular Other membrane receptor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28270411 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Renal fibrosis
Process I
Process II myofibroblasts activation
Process III prevenet collagen deposition
Mechanism Targeting Wnt/b-catenin signaling

Reference Record 2

PubMed ID 26362519 Compound ID
CAS Name
Model mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 22911790 Compound ID
CAS Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism