Uniprot ID: | O75787 |
Secondary ID: | B7Z9I3 |
Symbol: | ATP6AP2 |
Other Name: | ATP6IP2,ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,ER-localized type I transmembrane adaptor,Embryonic liver differentiation factor 10,N14F,Reninprorenin receptor,Vacuolar ATP synthase membrane sector-associated protein M8-9,ATP6M8-9,V-ATPase M8.9 subunit |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Receptor |
Category I | Category II | Category III |
---|---|---|
Extracellular | Other membrane receptor |
Reference Record 1
PubMed ID | 28270411 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Renal fibrosis |
Process I | |||
Process II | myofibroblasts activation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting Wnt/b-catenin signaling |
Reference Record 2
PubMed ID | 26362519 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Cardiac fibrosis |
Process I | attenue inflammation | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 3
PubMed ID | 22911790 | Compound ID | |
CAS | Name | ||
Model | rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |