Macrophage receptor MARCO

Basic Information


Uniprot ID: Q9UEW3
Secondary ID: B4DW79, Q9Y5S3
Symbol: MARCO
Other Name: SCARA2,Macrophage receptor with collagenous structure,Scavenger receptor class A member 2
Class: Single Protein
Type: pro/anti-fibrotic
Molecular Function: Receptor


Target Classification


Category I Category II Category III
Extracellular Other membrane receptor

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 25953850 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III
Mechanism Targeting M2 polarization

Reference Record 2

PubMed ID 21769674 Compound ID
CAS Name
Model mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting ASK1/p38/NF-κB