Uniprot ID: | Q9UEW3 |
Secondary ID: | B4DW79, Q9Y5S3 |
Symbol: | MARCO |
Other Name: | SCARA2,Macrophage receptor with collagenous structure,Scavenger receptor class A member 2 |
Class: | Single Protein |
Type: | pro/anti-fibrotic |
Molecular Function: | Receptor |
Category I | Category II | Category III |
---|---|---|
Extracellular | Other membrane receptor |
Reference Record 1
PubMed ID | 25953850 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Pulmonary fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism | Targeting M2 polarization |
Reference Record 2
PubMed ID | 21769674 | Compound ID | |
CAS | Name | ||
Model | mice | Fibrosis Disease | Cardiac fibrosis |
Process I | attenue inflammation | ||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting ASK1/p38/NF-κB |