Metalloproteinase inhibitor 1

Basic Information

Uniprot ID: P01033
Secondary ID: Q14252, Q9UCU1
Symbol: TIMP1
Other Name: CLGI,Erythroid-potentiating activity,EPA,Fibroblast collagenase inhibitor,Collagenase inhibitor,Tissue inhibitor of metalloproteinases 1,TIMP-1
Class: Single Protein
Type: pro/anti-fibrotic
Molecular Function: Growth factor,Metalloenzyme inhibitor,Metalloprotease inhibitor,Protease inhibitor

Target Classification

Category I Category II Category III
Extracellular TIMP/MMP TIMP

Related Compound

Fibrosis Related Property

Reference Record 1

PubMed ID 23456624 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 21300026 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation
Process III
Mechanism

Reference Record 3

PubMed ID 16762003 Compound ID
CAS Name
Model mice,rat Fibrosis Disease Liver fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 4

PubMed ID 16507762 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation,cells apoptosis
Process III
Mechanism

Reference Record 5

PubMed ID 15616792 Compound ID
CAS Name
Model human Fibrosis Disease Muscle fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 6

PubMed ID 15364860 Compound ID
CAS Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism