Dipeptidyl peptidase 4

Basic Information

Uniprot ID:	P27487
Secondary ID:	Q53TN1
Symbol:	DPP4
Other Name:	ADCP2,ADABP,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,DPP IV,T-cell activation antigen CD26,TP103,,Dipeptidyl peptidase IV membrane form,Dipeptidyl peptidase IV soluble form,Dipeptidyl peptidase 4 membrane form,Dipeptidyl peptidase 4 soluble form,Dipeptidyl peptidase IV membrane form,Dipeptidyl peptidase IV soluble form
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Aminopeptidase,Hydrolase,Protease,Receptor,Serine protease

Target Classification

Category I	Category II	Category III
Extracellular	Extracellular enzyme	Protease

Related Compound

Target ID	Name	Interaction
D0153	Linagliptin	inhibitor
D0430	Vildagliptin	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	27083282	Compound ID	D0153
CAS	668270-12-0	Name	Linagliptin
Model	rat	Fibrosis Disease	Renal fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID	25830763	Compound ID	D0153
CAS	668270-12-0	Name	Linagliptin
Model	mice	Fibrosis Disease	Renal fibrosis
Process I
Process II	EMT
Process III
Mechanism

Reference Record 3

PubMed ID	18787107	Compound ID	D0430
CAS	274901-16-5	Name	Vildagliptin
Model	vitro,mice	Fibrosis Disease	Pancreatic fibrosis
Process I
Process II	cells proliferation,cells apoptosis
Process III	prevenet collagen deposition
Mechanism