| Uniprot ID: | P00749 |
| Secondary ID: | B4DPZ2 |
| Symbol: | PLAU |
| Other Name: | Urokinase-type plasminogen activator long chain A,Urokinase-type plasminogen activator short chain A,Urokinase-type plasminogen activator chain B |
| Class: | Single Protein |
| Type: | pro-fibrotic |
| Molecular Function: | Hydrolase,Protease,Serine protease |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Extracellular enzyme | Protease |
Reference Record 1
| PubMed ID | 28139758 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Idiopathic pulmonary fibrosis |
| Process I | regulate cytokines and growth factors | ||
| Process II | fibroblasts proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting IL-6-gp130-Stat3 | ||
Reference Record 2
| PubMed ID | 27262672 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | fibroblasts migration, fibroblasts proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||