Xanthine dehydrogenase/oxidase

Basic Information

Uniprot ID:	P47989
Secondary ID:	Q16681, Q16712, Q4PJ16
Symbol:	XDH
Other Name:	XDHA,XD,XO,Xanthine oxidoreductase,XOR
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Oxidoreductase

Target Classification

Category I	Category II	Category III
Extracellular	Extracellular enzyme	Oxidoreductase

Related Compound

Target ID	Name	Interaction
D0336	Allopurinol	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	22587612	Compound ID	D0336
CAS	315-30-0	Name	Allopurinol
Model	dog	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID	22194975	Compound ID	D0336
CAS	315-30-0	Name	Allopurinol
Model	mice	Fibrosis Disease	Renal fibrosis
Process I	attenue inflammation
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID	17332431	Compound ID	D0336
CAS	315-30-0	Name	Allopurinol
Model	mice	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism