| Uniprot ID: | P17813 |
| Secondary ID: | Q14248, Q14926, Q5T9C0 |
| Symbol: | ENG |
| Other Name: | END, |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: | Angiogenesis,Cell adhesion |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Surface antigen | CD antigen |
Reference Record 1
| PubMed ID | 25015075 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | myofibroblasts differentiation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β1 signaling | ||
Reference Record 2
| PubMed ID | 21344387 | Compound ID | |
| CAS | Name | ||
| Model | vitro | Fibrosis Disease | Systemic sclerosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β/Smad1 signaling | ||
Reference Record 3
| PubMed ID | 19576647 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Renal fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β1 and ALK5 | ||