| Uniprot ID: | P41159 |
| Secondary ID: | O15158, Q56A88 |
| Symbol: | LEP |
| Other Name: | OB,Obese protein,Obesity factor |
| Class: | Single Protein |
| Type: | pro-fibrotic |
| Molecular Function: |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Secreted protein | Hormone |
Reference Record 1
| PubMed ID | 28257569 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 2
| PubMed ID | 17686962 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
| Process I | attenue inflammation | ||
| Process II | myofibroblasts differentiation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β signaling | ||