| Uniprot ID: | O94907 |
| Secondary ID: | B2RC19 |
| Symbol: | DKK1 |
| Other Name: | Dickkopf-1,Dkk-1,hDkk-1,SK |
| Class: | Single Protein |
| Type: | anti-fibrotic |
| Molecular Function: | Developmental protein |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Secreted protein | Dickkopf family |
Reference Record 1
| PubMed ID | 28331224 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | regulate cytokines and growth factors | ||
| Process II | HSC activation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Wnt signaling | ||
Reference Record 2
| PubMed ID | 27670695 | Compound ID | |
| CAS | Name | ||
| Model | Fibrosis Disease | Joint fibrosis | |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 3
| PubMed ID | 19297557 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Renal fibrosis |
| Process I | |||
| Process II | myofibroblasts activation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Wnt/β-catenin signaling | ||