| Uniprot ID: | Q9UBP4 |
| Secondary ID: | A8K1I2, D3DQW1, Q9ULB7 |
| Symbol: | DKK3 |
| Other Name: | REIC |
| Class: | Single Protein |
| Type: | pro-fibrotic |
| Molecular Function: | Developmental protein |
| Category I | Category II | Category III |
|---|---|---|
| Extracellular | Secreted protein | Dickkopf family |
Reference Record 1
| PubMed ID | 27699213 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
| Process I | regulate cytokines and growth factors | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 2
| PubMed ID | 28458155 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Keloid |
| Process I | |||
| Process II | fibroblasts proliferation,fibroblasts apoptosis | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β1/Smad signaling pathway | ||