Collagen alpha-1(I) chain

Basic Information

Uniprot ID:	P02452
Secondary ID:	O76045
Symbol:	COL1A1
Other Name:	Alpha-1 type I collagen
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Calcium,Metal-binding

Target Classification

Category I	Category II	Category III
Extracellular	Secreted protein	Collagen related protein

Related Compound

Target ID	Name	Interaction
D0052	Halofuginone	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	16735800	Compound ID	D0052
CAS	55837-20-2	Name	Halofuginone
Model	vitro	Fibrosis Disease	Renal fibrosis
Process I
Process II	fibroblasts proliferation
Process III
Mechanism	Targeting MMP-2

Reference Record 2

PubMed ID	11705455	Compound ID	D0052
CAS	55837-20-2	Name	Halofuginone
Model	vitro,mice	Fibrosis Disease	Dermal fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism