Uniprot ID: | Q12841 |
Secondary ID: | A8K523 |
Symbol: | FSTL1 |
Other Name: | FRP,Follistatin-like protein 1 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | Heparin-binding |
Category I | Category II | Category III |
---|---|---|
Extracellular | Secreted protein |
Reference Record 1
PubMed ID | 28341862 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Pulmonary fibrosis |
Process I | attenue inflammation | ||
Process II | myofibroblasts accumulation,fibroblasts-to-myofibroblasts | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting NLRP3 inflammasome and IL-1β |
Reference Record 2
PubMed ID | 25584011 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Pulmonary fibrosis |
Process I | attenue inflammation | ||
Process II | myofibroblasts activation,myofibroblasts accumulation | ||
Process III | prevenet collagen deposition | ||
Mechanism |